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I need to send many items in a short time to a Riak-index in a JSON-file. The question is, is it best to use lists instead of arrays?
You can use the riak.put/get method which allows you to save a document as a JSON object.
There’s documentation here which details the arguments to the PUT/GET methods.
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Missense variants in *STK11* and *ATM* are two of the most common variants associated with GC.[@R23] Hereditary diffuse gastric cancer (HDGC) is associated with germline mutations in the *STK11* and *CDH1* genes, which define the *MAP3K1/Helicobacter pylori* disease (MATCH) syndrome. Mutations in *ATM* have also been identified in individuals diagnosed with HDGC.[@R24] In the present study, four missense variants in *STK11* and two in *ATM* were identified in the Korean GC cases with no evidence of Helicobacter pylori infection. However, only one individual with a *STK11* mutation was diagnosed with HDGC; unfortunately, no gastric cancer tissue was available for histological examination in this particular case. This may also be due to the small sample size of HDGC cases in our study. Given that we only included three diffuse type GC cases, this result should be interpreted with caution.
We identified four novel heterozygous variants in the *NEIL1* gene in the three familial diffuse type GC cases, and one novel heterozygous variant in the *FEN1* gene and a homozygous variant in the *APEX1* gene in the four sporadic diffuse type GC cases. No other high-risk variants were found in the sporadic diffuse type GC patients. Our results suggest that, in addition to the well-characterised familial non-cardia GC, screening for germline genetic mutations should be undertaken in patients diagnosed with sporadic diffuse type GC.
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